Himanshu Jain, materials science professor and director of the International Materials Institute for New Functionality in Glass, together with George Huang, professor and director of bioscience research at the University of Tennessee, have received an NSF grant to evaluate recently developed technology for the regeneration of damaged dentin and pulp tissue in an effort to ultimately cure dentin hypersensitivity, known as DH.
Currently available products provide only temporary relief from DH pain. Their treatment uses nano-macro porous glass fabrication technology and the application of a new class of bioactive materials to regenerate dental tissue. The resulting glasses, which have what is known as a tailored amorphous multiporous (TAMP) structure, promote the growth of bone as well as soft tissue.
The project will result in new TAMP compositions and establish their potential for the regeneration of damaged dentin and pulp tissue to cure DH.
The duo will work with a cell biologist with expertise in cell response to TAMP materials and a healthcare industry expert with experience in early-stage commercialization of biomedical products. Additionally, three graduate students will receive training in use-inspired research and practical problem-solving through a cross-disciplinary approach, combining materials engineering, cell biology, and dental science.